PhD
luweisi@hotmail.com
Dr. Weisi Lu received her Bachelor and Ph.D degree from Sun Yat-sen University, China in 2010 and 2015, respectively. She completed her training through a National joint-Ph.D program in Baylor College of Medicine, US from 2011 to 2014. In 2015, she joined the faculty of the State Key Laboratory of Ophthalmology as an Assistant Researcher. Dr. Lu has published scientific research papers in journals including Cancer Cell, Stem Cells, Experimental Cell Research, Cell Stem Cell, and Journal of Biological Chemistry. Her current research interests mainly focus on the functions of growth factors like PDGF-C and VEGF-B in regulating stem/progenitor cells development.
Publications
He Q, Kim H, Huang R, Lu W, Tang M, Shi F, Yang D, Zhang X, Huang J, Liu D, Songyang Z. The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation. Cell Stem Cell. 2015;17(3):273-86
Fang L*, Lu W*, Choi HH, Yeung SC, Tung JY, Hsiao CD, Fuentes-Mattei E, Menter D, Chen C, Wang L, Wang J, Lee MH. ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development. Cancer Cell. 2015;28(2):183-97 (* equal contribution)
Lu W, Fang L, Ouyang B, Zhang X, Zhan S, Feng X, Bai Y, Han X, Kim H, He Q, Wan M, Shi FT, Feng XH, Liu D, Huang J, Songyang Z. Actl6a protects embryonic stem cells from differentiating into primitive endoderm. Stem Cells. 2015;33(6):1782-93
Liu Y, Kim H, Liang J, Lu W, Ouyang B, Liu D, Songyang Z. The death-inducer obliterator 1 (Dido1) gene regulates embryonic stem cell self-renewal. J Biol Chem. 2014;289(8):4778-86
Han X, Liu D, Zhang Y, Li Y, Lu W, Chen J, Songyang Z. Akt regulates TPP1 homodimerization and telomere protection. Aging Cell. 2013;12(6):1091-9
Shi FT, Kim H, Lu W, He Q, Liu D, Goodell MA, Wan M, Songyang Z. Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells. J Biol Chem. 2013;288(29):20776-84
Wan M, Liang J, Xiong Y, Shi F, Zhang Y, Lu W, He Q, Yang D, Chen R, Liu D, Barton M, Songyang Z. The trithorax group protein Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells. J Biol Chem. 2013;288(7):5039-48
Lu W, Zhang Y, Liu D, Songyang Z, Wan M. Telomeres-structure, function, and regulation. Exp Cell Res. 2013;319(2):133-41
Huang J, Okuka M, Lu W, Tsibris JC, McLean MP, Keefe DL, Liu L. Telomere shortening and DNA damage of embryonic stem cells induced by cigarette smoke. Reprod Toxicol. 2013;35:89-95
